Puas Toxins Puas cuam tshuam rau cov leeg qaug zog hauv kev tsim lub cev? Yog los tsis yog! Vim li cas kev qaug zog nce sai thiab nws cuam tshuam li cas rau cov leeg loj hlob? Nws tau pom tias qaug zog tshwm sim los ntawm kev txuam nrog cov co toxins. Qhov no yog pab pawg loj ntawm cov tshuaj uas tsim los ntawm kev ua haujlwm ntawm lub cev. Txhua tus ntawm lawv yog sab lossis nruab nrab cov metabolites. Lub hauv paus tseem ceeb tau suav hais tias yog lactic thiab pyruvic acids. Hnub no peb yuav tshuaj xyuas seb cov co toxins raug tsim thiab yuav ua li cas nrog lawv.
Mechanism of Formation of Fatigue Toxins
Cov co toxins hnyav dhau los yog cov txiaj ntsig ntawm glycogen thiab cov piam thaj oxidation. Raws li qhov xwm txheej ib txwm muaj, cov tshuaj no tau muab faib ua dej thiab carbon dioxide thaum oxidation nrog oxygen. Txawm li cas los xij, nrog lub cev ua haujlwm siab, yuav tsum muaj oxygen ntau rau oxidation thiab nws qhov tsis muaj tshwm sim hauv cov ntshav.
Qhov no ua rau qhov tseeb tias glycogen thiab piam thaj tsis tuaj yeem tawg tag thiab ib feem ntawm cov carbohydrates tau hloov pauv mus rau hauv lactic thiab pyruvic acids. Nws tseem yuav tsum tau sau tseg tias nrog cov ntsiab lus siab ntawm lactic acid hauv cov ntshav, cov hlab ntshav thauj cov pa hauv lub cev raug thaiv, uas ua rau nws nyuaj rau cov tshuaj nkag mus rau hauv cov nqaij mos.
Vim li no, qaug zog nce zoo li avalanche - thaum cov pa tsis txaus, cov kua qaub tau tsim, uas ua rau nyuaj rau cov pa oxygen nkag mus rau cov cell. Lub cev tig mus rau cov txheej txheem tiv thaiv thiab hloov mus rau cov txheej txheem tsis muaj oxygen. Hauv cov leeg nqaij ntawm qee lub sijhawm, cov tshuaj tiv thaiv ntawm anoxic oxidation hauv kev sib piv nrog lub xeev ib txwm nce los ntawm ib txhiab. Tab sis thaum lub sijhawm txheej txheem no, glycogen thiab piam thaj kuj tseem tsis tuaj yeem tawg tag, thiab theem ntawm cov tshuaj lom tseem nce ntxiv.
Nrog qhov tsis txaus ntawm cov carbohydrates, lub cev tam sim hloov mus rau oxidation ntawm fatty acids, nrog rau glycerol. Qhov no tshwm sim tsis pub dhau 20 feeb tom qab pib kawm. Txij li thaum lub cev muaj qib qis ntawm cov piam thaj, cov rog rog tsis tuaj yeem ua kom oxidized tag thiab, vim li ntawd, hydroxybutyric acid, acetone, acetoacetic thiab acetobutyric acids sib sau hauv cov ntshav.
Qhov no hloov cov kua qaub sib npaug mus rau ib puag ncig acidic thiab ua rau tsim cov acidosis. Tus neeg koom nrog tseem ceeb hauv kev sib xyaw ntawm acidosis yog lactic acid. Ntau tus neeg ncaws pob tau paub txog lub xeev kev tsaug zog thiab kev qaug zog uas tshwm sim tom qab kev cob qhia. Lub txim loj rau qhov no yog qhov tseeb lactic acidosis.
Nws tuaj yeem kwv yees tau tias siv cov kua mis lactic sai dua, kev qaug zog sai dua yuav dhau mus. Tab sis qhov pib ntawm kev qaug zog tsis yog tsuas yog nyob ntawm qib ntawm cov khoom no. Qhov no kuj tseem cuam tshuam los ntawm kev cuam tshuam ntawm fermentation thiab putrefaction uas tshwm sim hauv cov hnyuv yog tias cov zaub mov tsis tau zom tag. Cov khoom lag luam ntawm cov txheej txheem no tseem nkag mus rau hauv cov ntshav thiab ua rau lub xeev qaug zog. Peb kuj tseem ceeb dawb radicals tsim thaum lub sij hawm oxygen oxidation. Cov tshuaj no yog tshuaj lom thiab ua rau cov cell puas sai. Hauv qib qis, lawv tsis tuaj yeem ua rau muaj kev phom sij loj. Txawm li cas los xij, thaum nws nce, cov dawb radicals khi rau cov rog rog thiab tsim cov roj fatty acids, uas yog ntau qhov kev txiav txim ntawm qhov muaj tshuaj lom ntau dua li cov dawb radicals lawv tus kheej.
Lub cev niaj hnub tawm tsam cov tshuaj phem no. Feem ntau ntawm cov co toxins raug tshem tawm thiab tawm ntawm lub cev los ntawm ob lub raum thiab txoj hnyuv. Ua ntej ntawd, lawv raug tshem tawm hauv lub siab. Lub cev tiv thaiv kab mob tiv thaiv qaug zog co toxins muaj zog, tab sis nws tuaj yeem pab tau.
Yuav ua li cas nrog cov co toxins qaug zog?
Muaj cov txheej txheem tshwj xeeb hauv lub cev los tswj kev ua haujlwm - gluconeogenesis. Yooj yim muab, nws suav nrog kev sib xyaw ntawm cov piam thaj, uas tuaj yeem tsim los ntawm cov khoom nruab nrab ntawm cov tshuaj tiv thaiv oxidative, xws li lactic acid.
Thaum lub sijhawm gluconeogenesis, cov kua qaub tau hloov pauv rov qab mus rau hauv cov piam thaj, uas yog qhov tseem ceeb rau kev ua haujlwm lub cev siab. Tsis tas li, cov piam thaj tuaj yeem tsim tawm los ntawm cov amino acid sib txuas, glycerol, fatty acids, thiab lwm yam. Cov tshuaj tiv thaiv gluconeogenesis tshwm sim hauv lub siab, thiab thaum twg, vim tias muaj cov khoom hnyav, lub cev no tsis tuaj yeem tiv taus, ob lub raum kuj txuas nrog nws. Yog tias tus kis las tsis muaj teeb meem kev noj qab haus huv, li ntawm 50% ntawm cov kua mis lactic tau hloov pauv los ntawm daim siab mus rau hauv cov piam thaj. Nrog kev siv zog ntau ntawm kev cob qhia, cov protein sib txuas tau tawg mus rau hauv cov amino acids, los ntawm cov piam thaj kuj tseem sib xyaw.
Rau kev ua tiav ntawm kev ua haujlwm ntawm gluconeogenesis, cov hauv qab no yuav tsum tau ua raws:
- Lub siab noj qab nyob zoo;
- Ua kom muaj kev sib haum xeeb-adrenal system, uas ua ke cov tshuaj hormones glucocorticoid;
- Kev nce ntxiv hauv lub zog ntawm gluconeogenesis, uas tsuas yog ua tau nrog kev ua haujlwm lub cev tas li.
Txij li thaum lactic acid tsis kam nkag mus rau hauv cov ntshav, nws tau siv tsis zoo hauv cov tshuaj gluconeogenesis. Vim li no, lub cev sim txo qhov sib xyaw ntawm cov tshuaj no. Piv txwv li, cov kws ncaws pob dhau los muaj txog li ib nrab ntawm qib lactic acid ntau dua li cov neeg ncaws pob tshiab.
Cov kws tshawb fawb tab tom sim nrhiav tshuaj uas yuav txhim kho cov txheej txheem ntawm gluconeogenesis. Amphetamines yog thawj zaug tau siv rau cov laj thawj no. Lawv tau ua tiav cov txheej txheem ntawm cov piam thaj sib xyaw, tab sis vim muaj qhov tsis zoo ntawm lub hauv paus paj hlwb, lawv tsis tuaj yeem siv tau ntev.
Steroids thiab glucocorticoids txhim kho cov txheej txheem ntawm gluconeogenesis. Tab sis lawv tau txwv txoj kev thiab lawv siv tsis tau tas li. Tam sim no, txhawm rau ua kom muaj kev tiv thaiv ntev, actoprotectors, piv txwv li, Bromantane, Vita-melatonin thiab Bemetil, tau pib siv dav heev. Ntawm cov tshuaj uas twb paub lawm, koj tseem tuaj yeem pom cov txhais lus zoo ntawm kev txhim kho cov tshuaj tiv thaiv gluconeogenesis, piv txwv li, Dibazol. Nws txaus rau cov neeg ncaws pob siv tsuas yog ib ntsiav tshuaj ntawm cov tshuaj no thaum nruab hnub. Xav txog glutamic acid, uas yuav tsum tau noj nyob rau hauv cov koob tshuaj loj, suav txij li 10 txog 25 milligrams txhua hnub.
Yog xav paub ntxiv txog qhov cuam tshuam ntawm co toxins ntawm qaug zog, saib ntawm no:
