Tshawb nrhiav vim li cas cov neeg tsim lub cev nquag txo cov ntshav qab zib. Thiab yuav ua li cas thiaj li ua kom tsis txhob ua rau lub cev tsis ua haujlwm. Niaj hnub no, cov neeg ncaws pob tau siv tsis yog tsuas yog insulin, tab sis kuj yog cov tshuaj sib xyaw uas txo qis qab zib hauv lub cev. Kawm paub txog kev siv cov khoom siv hluavtaws hypoglycemic hauv kev tsim lub cev.
Cov tshuaj insulin yog cov protein ntau sib xyaw hnyav hnyav uas tsuas yog ua haujlwm thaum siv niam txiv. Vim li no, cov tshuaj siv hluavtaws tau tsim los pab kho ntshav qab zib thaum noj qhov ncauj. Lawv tsuas tuaj yeem pab cov neeg muaj ntshav qab zib hom 2. Hnub no peb yuav tham txog kev siv cov khoom siv hluavtaws hypoglycemic hauv kev tsim lub cev.
Kev faib tawm ntawm cov tshuaj antihyperglycemic hluavtaws
- Biguanide derivatives - metformin thiab buformin.
- Sulfonylurea derivatives - glipizide, glipenclamide, amaryl, thiab lwm yam.
- Derivatives ntawm cov amino acid sib txuas - pateglinite, repaglinide.
- Alpha -glucosidase inhibitors - acarbose.
- Thiazolidinediones - pioglitazone thiab rosiglitazone.
Tam sim no cia peb tham luv luv txog ob qhov nrov tshaj plaws hluavtaws hypoglycemic cov neeg sawv cev hauv kev tsim lub cev.
Metformin
Hauv seem ntawm txoj hnyuv me, kwv yees li 60 feem pua ntawm kev ua haujlwm ntawm cov tshuaj tau nqus. Qhov siab tshaj plaws ntawm cov tshuaj tshwm sim tsis pub dhau 2-4 teev tom qab siv. Cov txheej txheem ntawm kev ua haujlwm ntawm Metformin yog ua los ntawm kev txwv tsis pub tsim cov tshuaj glucagon, ua kom cov piam thaj ntau ntxiv los ntawm cov nqaij hauv lub cev, ua kom qeeb ntawm glyconeogenesis hauv lub siab, thiab lwm yam.
Glibenclamide
Cov tshuaj ua rau cov txheej txheem ntawm platelet sib sau ua ke, thaiv ATP cov channel, ua rau cov cell puas thiab ua rau cov tshuaj insulin tso tawm.
Kev siv cov khoom siv hluavtaws hypoglycemic
Txawm hais tias cov khoom siv hluavtaws hypoglycemic hauv kev tsim lub cev tau nquag siv los ntawm cov kislas, tseem tsis muaj pov thawj tshawb fawb pov thawj ntawm lawv qhov ua tau zoo. Vim li no, qhov kev pheej hmoo ntawm kev phiv tshuaj ntau ntxiv. Lawv tau siv los tswj cov kev xav ntawm cov tshuaj insulin ntuj thiab cov ntaub so ntswg nkag mus rau cov tshuaj no.
Cov neeg ncaws pob ntseeg siab tias txawm hais tias lawv tuaj yeem ua rau muaj kev pheej hmoo hypoglycemia, qhov tshwm sim ntawm qhov no yog qis dua piv rau insulin. Tsis tas li ntawd, cov tshuaj tau ua pov thawj zoo heev. Lub cim tshiab kawg ntawm sulfonylurea derivatives muaj peev xwm ua ncaj qha rau ntawm cov hlwb ntawm cov txiav ua ke uas tsim cov tshuaj insulin. Ib qho ntxiv, lawv tuaj yeem ua rau cov tshuaj insulin rhiab heev ntawm cov ntaub so ntswg, txhim kho cov phab ntsa ntawm cov hlab ntshav, thiab ua kom cov ntshav ntws thiab cov ntshav zoo. Tag nrho cov no ua rau nrawm ntawm cov metabolism.
Kev siv cov khoom siv hluavtaws hypoglycemic hauv kev tsim lub cev yog xyaum ua kom tiav ob lub hom phiaj:
- Kev ua kom nrawm ntawm cov tshuaj insulin thiab ua kom nce ntxiv hauv kev nqus ntawm cov tshuaj hormones.
- Txhawm rau txhim kho kev ua haujlwm ntawm exogenous insulin.
Feem ntau, cov kis las siv Buformin thiab Glipenclamide. Tsis tas li, tsis ntev los no, cov kis las tau mob siab rau Metformin, uas, piv rau lwm cov tshuaj, muaj qhov ua tau zoo dua. Raws li lub hom phiaj ntawm kev siv cov tshuaj txo qis qabzib, cov kis las tuaj yeem faib ua ob pawg:
- Tsis txhob siv cov tshuaj insulin.
- Cov neeg uas xav txhim kho kev ua tau zoo ntawm cov tshuaj insulin.
Nws tseem yog qhov tseem ceeb kom nkag siab tias feem ntau cov tshuaj insulin thiab tshuaj uas txhim kho kev sib xyaw ntawm cov tshuaj no tau siv ua ke nrog AAS. Nrog rau kev siv cov tshuaj insulin no, nws cov txiaj ntsig tau nce ntxiv, tab sis yog tias koj tseem pib siv cov khoom siv hluavtaws hypoglycemic hauv kev tsim lub cev, tom qab ntawd qhov ua tau zoo ntawm cov tshuaj exogenous tuaj yeem nce txog tsib zaug.
Yog tias koj txiav txim siab siv pawg insulin thiab buformin, tom qab ntawd koj yuav tsum tau them nyiaj tshwj xeeb rau kev tswj cov ntshav qab zib. Nrog rau kev sib xyaw ntawm cov tshuaj no, kev pheej hmoo ntawm hypoglycemia nce ntau thiab koj yuav tsum nqa cov khoom qab zib nrog koj. Tsis tas li, Buformin feem ntau siv nrog kev qhia txog somatotropin, uas tseem ua rau nws muaj peev xwm ua kom muaj txiaj ntsig zoo ntawm kev loj hlob hormone hauv chav kawm.
Cov kws ncaws pob kuj tseem tuaj yeem siv Buformin thaum lub caij tawm thaum tsis muaj AAS mus. Qhov no tso cai rau koj kom muaj txiaj ntsig zoo ntxiv tom qab anabolic. Txhua yam tshuaj muaj qee qhov tshwm sim thiab cov tshuaj hypoglycemic tsis muaj qhov tshwj xeeb. Tab sis nws yuav tsum tau lees paub tias lawv muaj kev nyab xeeb ntau dua li insulin, tab sis thaum siv kom raug, lawv yuav ua pov thawj kom ua tau zoo xwb.
Buformin tau nquag siv ua ke nrog Clenbuterol ntawm theem kawg ntawm cov tshuaj steroid. Qhov no tso cai rau koj tswj hwm qib siab ntawm anabolism thaum thim cov tshuaj steroids. Txij li cov tshuaj no tau siv dav hauv kev ncaws pob, qhov no yog qhov taw qhia ntawm lawv qhov ua tau zoo. Yog tias koj ua raws txhua cov lus pom zoo rau lawv siv, tom qab ntawd kev kho mob tuaj yeem hloov pauv tag nrho kev siv cov tshuaj insulin.
Yog xav paub ntxiv txog Metmorphine, saib cov vis dis aus no:
